Pol III Promoters to Express Small RNAs: Delineation of Transcription Initiation

Pol III promoters such as U6 are commonly used to express small RNAs, including small interfering RNA, short hairpin RNA, and guide RNA, for the clustered regularly interspaced short palindromic repeats genome-editing system. However, whether the small RNAs were precisely expressed as desired has no...

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Bibliographic Details
Main Authors: Hongming Ma, Yonggan Wu, Ying Dang, Jang-Gi Choi, Junli Zhang, Haoquan Wu
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303018