Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse.

A microarray-based negative selection screen was performed to identify Salmonella enterica serovar Typhimurium (serovar Typhimurium) genes that contribute to long-term systemic infection in 129X1/SvJ (Nramp1(r)) mice. A high-complexity transposon-mutagenized library was used to infect mice intraperi...

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Bibliographic Details
Main Authors: Trevor D Lawley, Kaman Chan, Lucinda J Thompson, Charles C Kim, Gregory R Govoni, Denise M Monack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0020011