Piperine Attenuates TBI-Induced Seizures via Inhibiting Cytokine-Activated Reactive Astrogliosis

Piperine Attenuates TBI-Induced Seizures via Inhibiting Cytokine-Activated Reactive Astrogliosis

Peppers have been used in clinics for a long time and its major component, piperine (PPR), has been proven to be effective in the treatment of seizures. The purpose of this study was to investigate the effects of piperine on early seizures in mice after a traumatic brain injury (TBI) and to explore...

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Bibliographic Details
Main Authors: Yabei Song, Caiyun Cao, Qiuyue Xu, Simeng Gu, Fushun Wang, Xi Huang, Shijun Xu, Erxi Wu, Jason H. Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
piperine
traumatic brain injury
seizure
glial fibrillary acidic protein
astrocytes
glymphatic system
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00431/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00431/full

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