The Influence of Radiation on Bone and Bone Cells—Differential Effects on Osteoclasts and Osteoblasts

The bone is a complex organ that is dependent on a tight regulation between bone formation by osteoblasts (OBs) and bone resorption by osteoclasts (OCs). These processes can be influenced by environmental factors such as ionizing radiation (IR). In cancer therapy, IR is applied in high doses, leadin...

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Bibliographic Details
Main Authors: Anna-Jasmina Donaubauer, Lisa Deloch, Ina Becker, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/17/6377