Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver

Transgenic mice overexpressing growth hormone (GH) spontaneously develop liver tumors, including hepatocellular carcinoma (HCC), within a year. The preneoplastic liver pathology in these mice recapitulates that observed in humans at high risk of developing hepatic cancer. Although increased expressi...

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Bibliographic Details
Main Authors: María L Bacigalupo, Verónica G Piazza, Nadia S Cicconi, Pablo Carabias, Andrzej Bartke, Yimin Fang, Ana I Sotelo, Gabriel A Rabinovich, María F Troncoso, Johanna G Miquet
Format: Article
Language:English
Published: Bioscientifica 2019-07-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0292.xml