Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8+ Lymphocytes in a Heterologous Challenge Model

Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8+ Lymphocytes in a Heterologous Challenge Model

Toxoplasma gondii is a worldwide prevalent parasite of humans and animals. The global infection burden exceeds yearly one million disability-adjusted life years (DALY's) in infected individuals. Therefore, effective preventive measures should be taken to decrease the risk of infection in humans...

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Bibliographic Details
Main Authors: Malgorzata Jennes, Stéphane De Craeye, Bert Devriendt, Katelijne Dierick, Pierre Dorny, Eric Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Toxoplasma gondii
infection
pigs
IFN-γ
T lymphocytes
immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00232/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00232/full

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