Early life microbiome perturbation alters pulmonary responses to ozone in male mice

Abstract Early life changes in the microbiome contribute to the development of allergic asthma, but little is known about the importance of the microbiome for other forms of asthma. Ozone is a nonatopic asthma trigger that causes airway hyperresponsiveness and neutrophil recruitment to the lungs. Th...

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Bibliographic Details
Main Authors: Traci A. Brown, Hiroki Tashiro, David I. Kasahara, Youngji Cho, Stephanie A. Shore
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14290