Genetic diversity and levels of expression of factor H binding protein among carriage isolates of Neisseria meningitidis.

The prevention of meningococcal disease may be improved by recombinant vaccines such as 4CMenB and rLP2086 that target the factor H binding protein (fHbp), an immunogenic surface component of Neisseria meningitidis present as one of three variants. Whether such vaccines decrease carriage of invasive...

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Bibliographic Details
Main Authors: Ludovic Lemée, Eva Hong, Manuel Etienne, Ala-Eddine Deghmane, Valérie Delbos, Aude Terrade, Gilles Berthelot, Francois Caron, Muhamed-Kheir Taha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4172500?pdf=render