Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models

Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models

Patients with triple-negative breast cancer have few therapeutic strategy options. In this study, we investigated the effect of isoliquiritigenin (ISL) on the proliferation of triple-negative breast cancer cells. We found that treatment with ISL inhibited triple-negative breast cancer cell line (MDA...

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Bibliographic Details
Main Authors: Po-Han Lin, Yi-Fen Chiang, Tzong-Ming Shieh, Hsin-Yuan Chen, Chun-Kuang Shih, Tong-Hong Wang, Kai-Lee Wang, Tsui-Chin Huang, Yong-Han Hong, Sing-Chung Li, Shih-Min Hsia
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Antioxidants
Subjects:
isoliquiritigenin (isl)
triple-negative breast cancer
apoptosis
autophagy
Online Access:https://www.mdpi.com/2076-3921/9/3/228

Internet

https://www.mdpi.com/2076-3921/9/3/228

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