Evidence for Multiple Origins of De Novo Formed Vascular Smooth Muscle Cells in Pulmonary Hypertension: Challenging the Dominant Model of Pre-Existing Smooth Muscle Expansion
Vascular remodeling is a prominent feature of pulmonary hypertension. This process involves increased muscularization of already muscularized vessels as well as neo-muscularization of non-muscularized vessels. The cell-of-origin of the newly formed vascular smooth muscle cells has been a subject of...
Main Authors: | Xuran Chu, Negah Ahmadvand, Jin-San Zhang, Werner Seeger, Saverio Bellusci, Elie El Agha |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | International Journal of Environmental Research and Public Health |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-4601/18/16/8584 |
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