The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion

The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion

Background: Pre-clinical research with multi-potent adult progenitor cells (MAPC® cells, Multistem, Athersys Inc., Cleveland, Ohio) suggests their potential as an anti-inflammatory and immunomodulatory therapy in organ transplantation. Normothermic machine perfusion of the liver (NMP-L) has been pro...

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Bibliographic Details
Main Authors: Richard W. Laing, Samantha Stubblefield, Lorraine Wallace, Valerie D. Roobrouck, Ricky H. Bhogal, Andrea Schlegel, Yuri L. Boteon, Gary M. Reynolds, Anthony E. Ting, Darius F. Mirza, Philip N. Newsome, Hynek Mergental, Simon C. Afford
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
liver transplantation
organ preservation
organ donation
mesenchymal progenitor cells
machine perfusion
stem cell therapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01226/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01226/full

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