Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion.

Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion.

Bladder cancer is the fourth most common cause of cancer in males in the United States. Invasive behavior is a major determinant of prognosis. In this study, we identified mammalian target of rapamycin complex 2 (mTORC2) as a central regulator of bladder cancer cell migration and invasion. mTORC2 ac...

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Bibliographic Details
Main Authors: Sounak Gupta, Andrew M Hau, Jordan R Beach, Jyoti Harwalker, Elisabetta Mantuano, Steven L Gonias, Thomas T Egelhoff, Donna E Hansel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842329?pdf=render

Internet

http://europepmc.org/articles/PMC3842329?pdf=render

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