Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion.
Bladder cancer is the fourth most common cause of cancer in males in the United States. Invasive behavior is a major determinant of prognosis. In this study, we identified mammalian target of rapamycin complex 2 (mTORC2) as a central regulator of bladder cancer cell migration and invasion. mTORC2 ac...
Main Authors: | Sounak Gupta, Andrew M Hau, Jordan R Beach, Jyoti Harwalker, Elisabetta Mantuano, Steven L Gonias, Thomas T Egelhoff, Donna E Hansel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3842329?pdf=render |
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