Mineralocorticoid Receptor-Dependent Impairment of Baroreflex Contributes to Hypertension in a Mouse Model of Primary Aldosteronism

Primary aldosteronism (PA) is the most common cause of secondary hypertension. The paucity of good animal models hinders our understanding of the pathophysiology of PA and the hypertensive mechanism of PA remains incompletely known. It was recently reported that genetic deletion of TWIK-related acid...

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Bibliographic Details
Main Authors: Luo Shi, Fang Yuan, Xuefang Wang, Ri Wang, Kun Liu, Yanming Tian, Zan Guo, Xiangjian Zhang, Sheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01434/full