Pharmacological and molecular effects of platinum(II) complexes involving 7-azaindole derivatives.

The in vitro antitumour activity studies on a panel of human cancer cell lines (A549, HeLa, G-361, A2780, and A2780R) and the combined in vivo and ex vivo antitumour testing on the L1210 lymphocytic leukaemia model were performed on the cis-[PtCl2(naza)2] complexes (1-3) involving the 7-azaindole de...

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Bibliographic Details
Main Authors: Pavel Starha, Jan Hošek, Ján Vančo, Zdeněk Dvořák, Pavel Suchý, Igor Popa, Gabriela Pražanová, Zdeněk Trávníček
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948342?pdf=render