CryoEM visualization of an adenovirus capsid-incorporated HIV antigen.

CryoEM visualization of an adenovirus capsid-incorporated HIV antigen.

Adenoviral (Ad) vectors show promise as platforms for vaccine applications against infectious diseases including HIV. However, the requirements for eliciting protective neutralizing antibody and cellular immune responses against HIV remain a major challenge. In a novel approach to generate 2F5- and...

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Bibliographic Details
Main Authors: Justin W Flatt, Tara L Fox, Natalia Makarova, Jerry L Blackwell, Igor P Dmitriev, Elena A Kashentseva, David T Curiel, Phoebe L Stewart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498208?pdf=render

Internet

http://europepmc.org/articles/PMC3498208?pdf=render

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