Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome

Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease characterized by arterial and/or venous thrombosis, pregnancy morbidity in the presence of circulating “anti-phospholipid antibodies” (aPL). One of the main target antigens of aPL is β2-glycoprotein I (β2-GPI). APS may occur a...

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Bibliographic Details
Main Authors: Valeria Manganelli, Simona Truglia, Antonella Capozzi, Cristiano Alessandri, Gloria Riitano, Francesca Romana Spinelli, Fulvia Ceccarelli, Silvia Mancuso, Tina Garofalo, Agostina Longo, Guido Valesini, Maurizio Sorice, Fabrizio Conti, Roberta Misasi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
HMGB1
sRAGE
antiphospholipid syndrome
thrombosis
recurrent abortion
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00460/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00460/full

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