Functional reconstitution of a tunable E3-dependent sumoylation pathway in Escherichia coli.

SUMO (small ubiquitin-related modifier) is a reversible post-translational protein modifier that alters the localization, activity, or stability of proteins to which it is attached. Many enzymes participate in regulated SUMO-conjugation and SUMO-deconjugation pathways. Hundreds of SUMO targets are c...

Full description

Bibliographic Details
Main Authors: Sean P O'Brien, Matthew P DeLisa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3373507?pdf=render