<i>BARD1</i> Pathogenic Variants Are Associated with Triple-Negative Breast Cancer in a Spanish Hereditary Breast and Ovarian Cancer Cohort

<i>BARD1</i> Pathogenic Variants Are Associated with Triple-Negative Breast Cancer in a Spanish Hereditary Breast and Ovarian Cancer Cohort

Only a small fraction of hereditary breast and/or ovarian cancer (HBOC) cases are caused by germline variants in the high-penetrance breast cancer 1 and 2 genes (<i>BRCA1</i> and <i>BRCA2)</i>. BRCA1-associated ring domain 1 (<i>BARD1</i>), nuclear partner of <...

Full description

Bibliographic Details
Main Authors: Paula Rofes, Jesús del Valle, Sara Torres-Esquius, Lídia Feliubadaló, Agostina Stradella, José Marcos Moreno-Cabrera, Adriana López-Doriga, Elisabet Munté, Rafael de Cid, Olga Campos, Raquel Cuesta, Àlex Teulé, Èlia Grau, Judit Sanz, Gabriel Capellá, Orland Díez, Joan Brunet, Judith Balmaña, Conxi Lázaro
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
<i>BARD1</i>
breast cancer
triple-negative breast cancer
ovarian cancer
hereditary breast and ovarian cancer
moderate cancer risk
Online Access:https://www.mdpi.com/2073-4425/12/2/150

Internet

https://www.mdpi.com/2073-4425/12/2/150

Similar Items