Amino-Nogo Inhibits Optic Nerve Regeneration and Functional Recovery via the Integrin αv Signaling Pathway in Rats

Amino-Nogo Inhibits Optic Nerve Regeneration and Functional Recovery via the Integrin αv Signaling Pathway in Rats

Background: Nogo-A, a major myelin-associated inhibitor, can inhibit injured optic nerve regeneration. However, whether Amino-Nogo is the most important functional domain of Nogo-A remains unknown. This study aimed to identify the role of Amino-Nogo following optic nerve injury, and the mechanism of...

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Bibliographic Details
Main Authors: Yan Huo, Xiao-Lei Yin, Shu-Xing Ji, Huan Zou, Min Lang, Zheng Zheng, Xiao-Feng Cai, Wei Liu, Chun-Lin Chen, Yuan-Guo Zhou, Rong-Di Yuan, Jian Ye
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Amino-Nogo
Axonal regeneration
Optic nerve
Integrin
Signaling pathway
Online Access:http://www.karger.com/Article/FullText/369723

Internet

http://www.karger.com/Article/FullText/369723

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