Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration

Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration

Glioblastoma (GB) is the most common and the most aggressive form of brain tumor in adults, which currently lacks efficient treatment strategies. In this study, we investigated the therapeutic effect of function-blocking antibodies targeting integrin α10β1 on patient-derived-GB cell lines in vitro a...

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Bibliographic Details
Main Authors: Katarzyna Chmielarska Masoumi, Xiaoli Huang, Wondossen Sime, Anna Mirkov, Matilda Munksgaard Thorén, Ramin Massoumi, Evy Lundgren-Åkerlund
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
function-blocking antibody
Glioblastoma
integrin α10β1
collagen
migration
tumor growth
Online Access:https://www.mdpi.com/2072-6694/13/5/1184

Internet

https://www.mdpi.com/2072-6694/13/5/1184

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