Validation of a method to assess emphysema severity by spirometry in the COPDGene study

Abstract Background Standard spirometry cannot identify the predominant mechanism underlying airflow obstruction in COPD, namely emphysema or airway disease. We aimed at validating a previously developed methodology to detect emphysema by mathematical analysis of the maximal expiratory flow-volume (...

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Bibliographic Details
Main Authors: Mariaelena Occhipinti, Matteo Paoletti, James D. Crapo, Barry J. Make, David A. Lynch, Vito Brusasco, Federico Lavorini, Edwin K. Silverman, Elizabeth A. Regan, Massimo Pistolesi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-020-01366-4