Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model.

The dynamics of tumor burden, secreted proteins or other biomarkers over time, is often used to evaluate the effectiveness of therapy and to predict outcomes for patients. Many methods have been proposed to investigate longitudinal trends to better characterize patients and to understand disease pro...

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Bibliographic Details
Main Authors: Rui Zhao, Paul Catalano, Victor G DeGruttola, Franziska Michor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5516991?pdf=render