Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling

Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling

Abstract Background Prostate cancer development involves various mechanisms, which are poorly understood but pointing to epithelial mesenchymal transition (EMT) as the key mechanism in progression to metastatic disease. ABI1, a member of WAVE complex and actin cytoskeleton regulator and adaptor prot...

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Main Authors: Disharee Nath, Xiang Li, Claudia Mondragon, Dawn Post, Ming Chen, Julie R. White, Anita Hryniewicz-Jankowska, Tiffany Caza, Vladimir A. Kuznetsov, Heidi Hehnly, Tamara Jamaspishvili, David M. Berman, Fan Zhang, Sonia H. Y. Kung, Ladan Fazli, Martin E. Gleave, Gennady Bratslavsky, Pier Paolo Pandolfi, Leszek Kotula
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cell Communication and Signaling
Online Access:http://link.springer.com/article/10.1186/s12964-019-0410-y

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http://link.springer.com/article/10.1186/s12964-019-0410-y

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