LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11

<p>The transmembrane protein ADAM22 is expressed at high levels in the brain. From its molecular structure, ADAM22 is thought to be an adhesion molecule or a receptor because it has functional disintegrin-like and cysteine-rich sequences in its ectodomain. The phenotypic analysis of ADAM22-def...

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Bibliographic Details
Main Author: Koji Sagane, Yasushi Ishihama, Hachiro Sugimoto
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v04p0387.htm