Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking

Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking

Receptor tyrosine kinases (RTKs) are membrane-based sensors that enable rapid communication between cells and their environment. Evidence is now emerging that interdependent regulatory mechanisms, such as membrane trafficking, ubiquitination, proteolysis and gene expression, have substantial effects...

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Bibliographic Details
Main Authors: William R. Critchley, Caroline Pellet-Many, Benjamin Ringham-Terry, Michael A. Harrison, Ian C. Zachary, Sreenivasan Ponnambalam
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cells
Subjects:
receptor tyrosine kinases
ubiquitin
ubiquitin ligases
de-ubiquitinases
signal transduction
trafficking
proteolysis
Online Access:http://www.mdpi.com/2073-4409/7/3/22

Internet

http://www.mdpi.com/2073-4409/7/3/22

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