Isolation and chimerization of a highly neutralizing antibody conferring passive protection against lethal Bacillus anthracis infection.

Several studies have demonstrated that the passive transfer of protective antigen (PA)-neutralizing antibodies can protect animals against Bacillus anthracis infection. The standard protocol for the isolation of PA-neutralizing monoclonal antibodies is based upon a primary selection of the highest P...

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Bibliographic Details
Main Authors: Ronit Rosenfeld, Hadar Marcus, Einat Ben-Arie, Bat-El Lachmi, Adva Mechaly, Shaul Reuveny, Orit Gat, Ohad Mazor, Arie Ordentlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2710523?pdf=render