Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells.

The spiral ganglion neurons constitute the primary connection between auditory hair cells and the brain. The spiral ganglion afferent fibers and their synapse with hair cells do not regenerate to any significant degree in adult mammalian ears after damage. We have investigated gene expression change...

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Bibliographic Details
Main Authors: Chen-Chi Wu, Aurore Brugeaud, Richard Seist, Hsiao-Chun Lin, Wei-Hsi Yeh, Marco Petrillo, Giovanni Coppola, Albert S B Edge, Konstantina M Stankovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238578