RNA methylation by the MIS complex regulates a cell fate decision in yeast.

For the yeast Saccharomyces cerevisiae, nutrient limitation is a key developmental signal causing diploid cells to switch from yeast-form budding to either foraging pseudohyphal (PH) growth or meiosis and sporulation. Prolonged starvation leads to lineage restriction, such that cells exiting meiotic...

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Bibliographic Details
Main Authors: Sudeep D Agarwala, Hannah G Blitzblau, Andreas Hochwagen, Gerald R Fink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3369947?pdf=render