Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery

Abstract We demonstrate an in vitro microfluidic cell culture platform that consists of periodic 3D hydrogel compartments with controllable shapes. The microchip is composed of approximately 500 discontinuous collagen gel compartments locally patterned in between PDMS pillars, separated by microflui...

Full description

Bibliographic Details
Main Authors: Burcu Gumuscu, Hugo J. Albers, Albert van den Berg, Jan C. T. Eijkel, Andries D. van der Meer
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01944-5