Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.

Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.

AIMS/HYPOTHESIS: Bile acid sequestrants (BAS) reduce plasma glucose levels in type II diabetics and in murine models of diabetes but the mechanism herein is unknown. We hypothesized that sequestrant-induced changes in hepatic glucose metabolism would underlie reduced plasma glucose levels. Therefore...

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Bibliographic Details
Main Authors: Maxi Meissner, Hilde Herrema, Theo H van Dijk, Albert Gerding, Rick Havinga, Theo Boer, Michael Müller, Dirk-Jan Reijngoud, Albert K Groen, Folkert Kuipers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210115?pdf=render

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http://europepmc.org/articles/PMC3210115?pdf=render

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