Size control in mammalian cells involves modulation of both growth rate and cell cycle duration

The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.

Bibliographic Details
Main Authors: Clotilde Cadart, Sylvain Monnier, Jacopo Grilli, Pablo J. Sáez, Nishit Srivastava, Rafaele Attia, Emmanuel Terriac, Buzz Baum, Marco Cosentino-Lagomarsino, Matthieu Piel
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05393-0