Chromatin Insulators and Topological Domains: Adding New Dimensions to 3D Genome Architecture

The spatial organization of metazoan genomes has a direct influence on fundamental nuclear processes that include transcription, replication, and DNA repair. It is imperative to understand the mechanisms that shape the 3D organization of the eukaryotic genomes. Chromatin insulators have emerged as...

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Bibliographic Details
Main Authors: Navneet K. Matharu, Sajad H. Ahanger
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/6/3/790