Effects of phosphorylation sites of FoxO1 on protein synthesis and proteolysis in rat skeletal muscle cells exposure to hypoxia

Objective To investigate the effects of different phosphorylation sites of FoxO1 on protein synthesis and proteolysis in rat skeletal muscle L6 cells under the condition of hypoxia. Methods Adenoviral vectors (FoxO1, FoxO1T24A/D, FoxO1S250A/D, and FoxO1AS313A/D) were constructed, and then used to in...

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Bibliographic Details
Main Authors: JIA Jie, FU Pengyu, ZHU Rongxin, XU Chunyan2, GONG Lijing
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-08-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202003281.htm