Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis [version 1; referees: 2 approved]

It is well known that infiltration of pathogenic T-cells plays an important role in psoriasis pathogenesis. However, the antigen specificity of these activated T-cells is relatively unknown. Previous studies using T-cell receptor polymerase chain reaction technology (TCR-PCR) have suggested there ar...

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Bibliographic Details
Main Authors: Jamie L. Harden, David Hamm, Nicholas Gulati, Michelle A. Lowes, James G. Krueger
Format: Article
Language:English
Published: F1000 Research Ltd 2015-08-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-460/v1