Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis [version 1; referees: 2 approved]
It is well known that infiltration of pathogenic T-cells plays an important role in psoriasis pathogenesis. However, the antigen specificity of these activated T-cells is relatively unknown. Previous studies using T-cell receptor polymerase chain reaction technology (TCR-PCR) have suggested there ar...
Main Authors: | Jamie L. Harden, David Hamm, Nicholas Gulati, Michelle A. Lowes, James G. Krueger |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2015-08-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/4-460/v1 |
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