Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists

Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists

Inactivation of Rho GTPase with a single intraocular injection of Rho antagonists stimulates survival and regeneration of retinal ganglion cells (RGCs) after optic nerve injury. However, this effect is short-lived. Here we tested the impact of multiple injections of C3-like Rho antagonists on RGC vi...

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Bibliographic Details
Main Authors: J. Bertrand, A. Di Polo, L. McKerracher
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Neurobiology of Disease
Subjects:
Rho GTPase
Retinal ganglion cell (RGC)
Optic nerve
Neuroprotection
Regeneration
C3
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002117

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http://www.sciencedirect.com/science/article/pii/S0969996106002117

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