Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Abstract Background Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high sensitivity. HRP2 tests can remain positive for weeks after treatment, limiting their specificity and usefuln...

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Bibliographic Details
Main Authors: Matthew E. Coldiron, Bachir Assao, Céline Langendorf, Nathan Sayinzoga-Makombe, Iza Ciglenecki, Roberto de la Tour, Erwan Piriou, Mahaman Yarima Bako, Ann Mumina, Ousmane Guindo, Anne-Laure Page, Rebecca F. Grais
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Malaria Journal
Subjects:
Malaria
Rapid diagnostic test
Plasmodium lactate dehydrogenase
Histidine-rich protein 2
Niger
Online Access:https://doi.org/10.1186/s12936-019-3079-1

Internet

https://doi.org/10.1186/s12936-019-3079-1

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