PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type 2 diabetes (T2D). The role of pancreatic islet function in this restoration of normoglycemia has not been fully elucidated. Using the diabetic Goto-Kakizaki (GK) rat model, we demonstrate that RYGB...

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Bibliographic Details
Main Authors: Reshma D. Ramracheya, Laura J. McCulloch, Anne Clark, David Wiggins, Helene Johannessen, Magnus Kringstad Olsen, Xing Cai, Chun-Mei Zhao, Duan Chen, Patrik Rorsman
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716303977

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http://www.sciencedirect.com/science/article/pii/S2211124716303977

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