In situ thermal ablation augments antitumor efficacy of adoptive T cell therapy

In situ thermal ablation augments antitumor efficacy of adoptive T cell therapy

Purpose: The aim of this study is to investigate whether radiofrequency ablation (RFA) improves the efficacy of adoptive T cell immunotherapy in preclinical mouse cancer models. Method: Mice implanted subcutaneously (sc) with syngeneic colon adenocarcinoma or melanoma were treated with sub-curative...

Full description

Bibliographic Details
Main Authors: Fumito Ito, Trupti D. Vardam, Michelle M. Appenheimer, Kevin H. Eng, Sandra O. Gollnick, Jason B. Muhitch, Sharon S. Evans
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:International Journal of Hyperthermia
Subjects:
radiofrequency ablation
t cells
trafficking
adoptive cell therapy
tumor-draining lymph node
Online Access:http://dx.doi.org/10.1080/02656736.2019.1653500

Internet

http://dx.doi.org/10.1080/02656736.2019.1653500

Similar Items