ANSID: a Solid-Phase Proteomic Approach for Identification and Relative Quantification of Aromatic Nitration Sites

ANSID: a Solid-Phase Proteomic Approach for Identification and Relative Quantification of Aromatic Nitration Sites

Nitration of tyrosine and other aromatic amino acid residues in proteins occurs in the setting of inflammatory, neurodegenerative and cardiovascular diseases – importantly, this modification has been implicated in the pathogenesis of diverse diseases and the physiological process of tissue aging. To...

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Bibliographic Details
Main Authors: Tal eNuriel, Julia eWhitehouse, Yuliang eMa, Emily eMercer, Neil eBrown, Steven S Gross
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Chemistry
Subjects:
Nitric Oxide
Proteomics
nitrosative stress
post-translational modifications
peroxynitrite
nitrotyrosine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00070/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00070/full

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