Cx43-hemichannel function and regulation in physiology and pathophysiology: insights from the bovine corneal endothelial cell system and beyond

Cx43-hemichannel function and regulation in physiology and pathophysiology: insights from the bovine corneal endothelial cell system and beyond

Intercellular communication in primary bovine corneal endothelial cells (BCECs) is mainly driven by the release of extracellular ATP through Cx43 hemichannels. Studying the characteristics of Ca2+-wave propagation in BCECs, an important form of intercellular communication, in response to physiologic...

Full description

Bibliographic Details
Main Authors: Catheleyne eD'hondt, Jegan eIyyathurai, Bernard eHimpens, Luc eLeybaert, Geert eBultynck
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Physiology
Subjects:
intercellular communication
hemichannels
loop/tail interactions
actin/myosin contractility
selective inhibition of Cx43 hemichannels
corneal endothelial cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00348/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00348/full

Similar Items