Transcription Repressor Hes1 Contributes to Neuropathic Pain Development by Modifying CDK9/RNAPII-Dependent Spinal <i>mGluR5 </i>Transcription

Diverse transcriptional controls in the dorsal horn have been observed in pain hypersensitivity. However, the understanding of the exact causes and mechanisms of neuropathic pain development is still fragmentary. Here, the results demonstrated nerve injury decreased the expression of spinal hairy an...

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Bibliographic Details
Main Authors: Ming-Chun Hsieh, Hsien-Yu Peng, Yu-Cheng Ho, Cheng-Yuan Lai, Jen-Kun Cheng, Gin-Den Chen, Tzer-Bin Lin
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/17/4177