Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase

<p>Abstract</p> <p>Background</p> <p>The mechanisms involved in the induction and regulation of inflammation resulting in dopaminergic (DA) neurotoxicity in Parkinson's disease (PD) are complex and incompletely understood. Microglia-mediated inflammation has recent...

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Bibliographic Details
Main Authors: Wilson Belinda, Zhang Wei, Xu Zongli, Qian Li, Hong Jau-Shyong, Flood Patrick M
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/23