Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Summary: The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the...

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Bibliographic Details
Main Authors: Yun Song, Lisbeth Dagil, Louise Fairall, Naomi Robertson, Mingxuan Wu, T.J. Ragan, Christos G. Savva, Almutasem Saleh, Nobuhiro Morone, Micha B.A. Kunze, Andrew G. Jamieson, Philip A. Cole, D. Flemming Hansen, John W.R. Schwabe
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472030125X

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http://www.sciencedirect.com/science/article/pii/S221112472030125X

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