High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry

Real-time deformability cytometry (RT-DC) is used for mechanical cell phenotyping but is limited to a single snapshot per cell and can only measure elastic modulus. Here the authors introduce dynamic RT-DC which can measure elasticity and viscosity in single cells by following dynamic cell shape cha...

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Bibliographic Details
Main Authors: Bob Fregin, Fabian Czerwinski, Doreen Biedenweg, Salvatore Girardo, Stefan Gross, Konstanze Aurich, Oliver Otto
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08370-3