The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

Antigen presentation is a cellular process that involves a number of steps, beginning with the production of peptides by proteolysis or aberrant synthesis and the delivery of peptides to cellular compartments where they are loaded on MHC class I (MHC-I) or MHC class II (MHC-II) molecules. The select...

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Bibliographic Details
Main Authors: Kannan Natarajan, Jiansheng Jiang, Nathan A. May, Michael G. Mage, Lisa F. Boyd, Andrew C. McShan, Nikolaos G. Sgourakis, Ad Bax, David H. Margulies
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
major histocompatibility complex
T cell receptor
tapasin
transporter associated with antigen presentation
TAP-binding protein
related
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01657/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01657/full

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