Identifying the optimal donor for natural killer cell adoptive therapy to treat paediatric B‐ and T‐cell acute lymphoblastic leukaemia

Identifying the optimal donor for natural killer cell adoptive therapy to treat paediatric B‐ and T‐cell acute lymphoblastic leukaemia

Abstract Objectives Natural killer (NK) cells are an attractive source of cells for an ‘off the shelf’ cellular therapy because of their innate capacity to target malignant cells, and ability to be transferred between donors and patients. However, since not all NK cells are equally effective at targ...

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Bibliographic Details
Main Authors: Bree Foley, Clara Ta, Samantha Barnes, Emma deJong, Michelle Nguyen, Laurence C Cheung, Anthony Buzzai, Teagan Wagner, Ben Wylie, Sonia Fernandez, Mark Cruickshank, Raelene Endersby, Ursula Kees, Jason Waithman
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
acute lymphoblastic leukaemia
cellular therapy
cytomegalovirus
natural killer cells
Online Access:https://doi.org/10.1002/cti2.1151

Internet

https://doi.org/10.1002/cti2.1151

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