Does DNA methylation of PPARGC1A influence insulin action in first degree relatives of patients with type 2 diabetes?

Does DNA methylation of PPARGC1A influence insulin action in first degree relatives of patients with type 2 diabetes?

Epigenetics may play a role in the pathophysiology of type 2 diabetes (T2D), and increased DNA methylation of the metabolic master regulator peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) has been reported in muscle and pancreatic islets from T2D patients and in musc...

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Bibliographic Details
Main Authors: Linn Gillberg, Stine C Jacobsen, Rasmus Ribel-Madsen, Anette Prior Gjesing, Trine W Boesgaard, Charlotte Ling, Oluf Pedersen, Torben Hansen, Allan Vaag
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3591301?pdf=render

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http://europepmc.org/articles/PMC3591301?pdf=render

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