Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.

Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.

Host genetic factors may be important determinants of HIV-1 sexual acquisition. We performed a genome-wide association study (GWAS) for host genetic variants modifying HIV-1 acquisition and viral control in the context of a cohort of African HIV-1 serodiscordant heterosexual couples. To minimize mis...

Full description

Bibliographic Details
Main Authors: Jairam R Lingappa, Slavé Petrovski, Erin Kahle, Jacques Fellay, Kevin Shianna, M Juliana McElrath, Katherine K Thomas, Jared M Baeten, Connie Celum, Anna Wald, Guy de Bruyn, James I Mullins, Edith Nakku-Joloba, Carey Farquhar, Max Essex, Deborah Donnell, James Kiarie, Bart Haynes, David Goldstein, Partners in Prevention HSV/HIV Transmission Study Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3236203?pdf=render

Internet

http://europepmc.org/articles/PMC3236203?pdf=render

Similar Items